Methods to raise... Antibodies are routinely used to study the activity of transcription factors, using various in vitro and in vivo approaches such as electrophoretic mobility shift assay, enzyme-linked immunosorbent assay, genome-wide method analysis coupled with next generation sequencing, or mass spectrometry. Email: martina.jones@uq.edu.au . Scientific Reports, 5 (37348) 37348, 37348. doi: 10.1038/srep37348, Biosimilars approved for treatment of inflammatory rheumatological diseases, Mahler, Stephen M., Wardiana, Andri, Jones, Martina L., De Bakker, Christopher J., Graham, Garry G. and Howard, Christopher B. All rights reserved. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. Therapy using systemic deli... Membrane proteins are attractive targets for monoclonal antibody (mAb) discovery and development. One possible explanation for the vulnerability of current antibodies used in RDTs is their p... BACKGROUND: Human embryonic kidney-293 (HEK-293) cells are commonly used as a transient expression host but their application in stable therapeutic protein production is limited. Developing a Therapeutic Anti - Dendritic Cell Antibody to Prevent Graft Versus Host Disease. Taylor, Karin, Howard, Christopher B., Jones, Martina L., Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P. and Mahler, Stephen M. (2014). Martina Louise Jones CD117 (c-Kit) is a tyrosine kinase receptor that is overexpressed in multiple dog tumors. Milk folate-binding protein; ligand-binding properties and polymerization properties. Engineering bispecific antibodies for targeted delivery of cytotoxin-loaded nanoparticles to tumour cells, For Media assistance please contact The Office of Marketing and Communications, (07) 3365 1120, Privacy & Terms of use Nanocell targeting using engineered bispecific antibodies.. mAbs, 7 (1), 53-65. doi: 10.4161/19420862.2014.985952, Monoclonal antibody-targeted polymeric nanoparticles for cancer therapy - future prospects, Goodall, Stephen, Jones, Martina L. and Mahler, Stephen (2014). 33rd Annual Scientific Meeting of the Transplantation Society of Australia and new Zealand, Canberra, ACT Australia, 21-23 June 2015. Thus, CD117 is an important target for cancer treatment in dogs and for comparative oncology studies. 16/2016). Several epitope regions were predict... Human Chaperonin 10 (hCpn10) was utilised as a novel scaffold for presenting peptides of therapeutic and diagnostic significance. Martina has 3 jobs listed on their profile. National Biologics Facility - Queensland Node. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A. Journal of Immunological Methods, 354 (1-2), 85-90. doi: 10.1016/j.jim.2010.02.001, Use of chimeric antibodies as positive controls in an enzyme-linked immunosorbent assay for diagnosis of scrub typhus (infection by orientia tsutsugamushi), Jones, Martina L. and Barnard, Ross (2007). Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10. to UQ, UQ Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. In this double-blind, placebo-controlled, single-centre, dose-escalation, phase 1... Phage display methodologies offer a versatile platform for the isolation of single-chain Fv (scFv) molecules which may be rebuilt into monoclonal antibodies. Poster Board III-491 Flower, R., Ekman, S., Mahler, S., Jones, M., Malde, A. K. and Bui, X. Plos One, 12 (10) e0186137, e0186137. ), London, United Kingdom: Lippincott Williams & Wilkins. Molecular dynamic simulations and protein sizing analyses identified a peptide linker (P1) optimal for the formation of the quarternary hCpn10 heptamer structure. Ju, Xinsheng, Elgundi, Zehra, Verma, Nirupama, Silveira, Pablo, Fromm, Phillip, Alingcastre, Renz, Munster, David, Seldon, Therese, Sheng, Yonghua, Jones, Martina, Munro, Trent, Mahler, Stephen, Barnard, Ross, Vu, Ai, Lo, Tsun Ho, Shahin, Kifah, Clark, Georgina, Larsen, Stephen, Bradstock, Kenneth and Hart, Derek (2015).