Published on behalf of the European Society of Cardiology. In younger men, a presumptive cause of sudden cardiac death remained undetermined in only 24% (P =.025 vs younger women), and coronary artery disease accounted for 40% of cases. Autopsy examination is the mainstay of diagnosis in cases of sudden death and can exclude non‐cardiac causes of death, such as pulmonary embolism, aortic dissection and intracranial haemorrhage. Key role of the molecular autopsy in sudden unexpected death. In younger women, despite autopsy and detailed cardiac pathologic examination, an attributable cause of sudden cardiac death was not determined in 50% of cases; a 2-fold increase compared to men of the same age. Due to under-representation of younger adults in published autopsy series, etiologies of sudden cardiac death merit further investigation. Haïssaguerre M, Duchateau J, Dubois R, Hocini M, Cheniti G, Sacher F, Lavergne T, Probst V, Surget E, Vigmond E, Welte N, Chauvel R, Derval N, Pambrun T, Jais P, Nademanee W, Bernus O. JACC Clin Electrophysiol. Sudden cardiac death is described as death that occur within the 1st hour of the onset of the symptoms or death within the 24 hours of the onset of symptoms in unwitnessesed deaths. Afr Health Sci. Sudden unexplained deaths (SUD) are those where no cause is found after detailed premorbid history and a complete autopsy with macroscopic, histological and toxicology assessment. Chin J Traumatol. 2004;350:2438–510. Conclusion: This site needs JavaScript to work properly. Int J Cardiol. Tseng ZH, Olgin JE, Vittinghoff E, Ursell PC, Kim AS, Sporer K, Yeh C, Colburn B, Clark NM, Khan R, Hart AP, Moffatt E. Circulation. HHS Background: 1994 Mar;87(3):319-24. 2010;122(6):597–602. Please enable it to take advantage of the complete set of features! Get the latest research from NIH: https://www.nih.gov/coronavirus. -, Pouleur A-C, Barkoudah E, Uno H, et al. The major cardiac pathology resulting in sudden death was coronary artery disease (n-116; 56.86%) and myocardial infarction (n-104; 50.9%). Arch Mal Coeur Vaiss. Forensic Sci Int. The sudden death of a young, apparently fit and healthy person is amongst the most challenging scenarios in clinical medicine. In up to 30% of young SCD, no cause of death is identified at postmortem, so-called autopsy-negative or sudden arrhythmic death syndrome (SADS). Potential Risk Factors of Death in Multiple Trauma Patients. Methods: Epub 2010 Oct 30. Prevalence and pattern of cardiovascular-related causes of out-of- hospital deaths in Lagos, Nigeria. Epub 2014 Mar 6.  |  Male to female ratio was around 10:1. Aim Sudden unexplained nocturnal death syndrome (SUNDS) has been linked to the Brugada syndrome. 2019 Aug;22(4):212-218. doi: 10.1016/j.cjtee.2019.01.012. Shock to the Heart: Psychosocial Implications and Applications of Sudden Cardiac Death in the Young. 2020 Jun;6(6):591-608. doi: 10.1016/j.jacep.2020.03.010. CAD: coronary artery disease; MI: myocardial infarction; VR: ventricular…, Percentage of blockage of coronary artery, NLM -, Hurt RD, Weston SA, Ebbert JO, et al. USA.gov. Incidence of sudden cardiac death (SCD) has been steadily increasing all over the world. Europace. Get the latest public health information from CDC: https://www.coronavirus.gov. 2006 Jan 27;156(2-3):138-44. doi: 10.1016/j.forsciint.2004.12.024. Please enable it to take advantage of the complete set of features! Sudden cardiac death (SCD) is a devastating and tragic outcome of a number of underlying cardiovascular diseases. We observed no difference in having had a cardiac assessment prior to death compared to being in the group with non-diagnostic autopsy findings or having a blank autopsy (p = 0.79). A cause of Sudden Cardiac Deaths on Autopsy Findings; a Four-Year Report. Methods: We reviewed autopsy and detailed cardiac pathologic findings in younger women (age 35-44 years) from a 270-patient, 13-year (1984-1996) autopsy series of sudden cardiac death, and performed comparisons with findings in age-matched men. NIH Get the latest public health information from CDC: https://www.coronavirus.gov. The role of molecular autopsy in unexplained sudden cardiac death. 2018 Jun 19;137(25):2689-2700. doi: 10.1161/CIRCULATIONAHA.117.033427. doi: 10.1371/journal.pone.0237731. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error, Distribution of various causes of death both natural and unnatural from Jan 2008 to Dec 2011, Type of cardiac pathology.